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Type d'Item :Item, Contrôle De Qualité Et Analyse Physico-Chimiques De Deux Préparations A Usage Antiseptique « Cas De L’alcool Iodée Et De L’eau Oxygenée »(Université Sétif1 Ferhat Abbas. Faculté de Médecine., 2026) KHERIS , Nour El Imene Selsabil; KHENCHOUCHE , Rayene; DAAS , Yasmine; ZEBAR , Maroua ( Encadrant )The quality control of antiseptic preparations is essential to ensure the safety and effectiveness of products intended to eliminate or inhibit microorganisms on the skin and mucous membranes. It involves a series of physicochemical and microbiological tests designed to verify compliance with regulatory standards and to guarantee optimal antiseptic activity during healthcare procedures. The present study aimed to evaluate the quality and regulatory compliance of two commonly used antiseptics, namely iodinated alcohol and hydrogen peroxide, obtained from different pharmaceutical laboratories. For iodinated alcohol, samples E1, E3, and E4 failed to comply with the density specifications established by the National Formulary (2007). The acidity test indicated that sample E3 was compliant, reflecting satisfactory chemical stability and appropriate preparation and storage conditions. However, all analyzed samples were found to be non-compliant with the iodine assay, exhibiting significantly lower iodine concentrations than required. This deficiency may be attributed to the volatilization of molecular iodine during storage. Regarding hydrogen peroxide, all tested samples complied with Identification Test A, confirming the presence of hydrogen peroxide and indicating that the concentration of reducing substances remained within the limits specified by the pharmacopoeial monograph. In contrast, sample E3 did not meet the requirements of Identification Test B. The acidity test revealed that samples E2, E3, and E5 complied with the established standards, whereas samples E1 and E4 showed non-compliance, likely due to the presence of excessive acidic impurities. The determination of hydrogen peroxide content by manganimetric titration demonstrated that none of the analyzed samples reached the required concentration, indicating non-compliance with quality specifications. This result can be mainly explained by the intrinsic instability of hydrogen peroxide, a compound highly sensitive to environmental factors such as light and heat. In conclusion, quality control of antiseptic preparations constitutes a crucial component of healthcare safety and infection prevention. It ensures that antiseptic products possess adequate antimicrobial activity while maintaining their safety for use on living tissuesType d'Item :Item, Impact De Dosage Quantitatif De Bcr:abl Dans Le Suivi Des LMC(Université Sétif1 Ferhat Abbas. Faculté de Médecine., 2026) BENMAKHLOUF , Achrafnadjib; BENNIA , Mohamed Khalil; BENCHALAL , Toumia (Encadrant )Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm characterized by the Philadelphia chromosome (Ph), arising from the reciprocal translocation t(9;22)(q34;q11.2), which generates the BCR-ABL1 fusion gene encoding a constitutively active tyrosine kinase. This oncoprotein aberrantly activates RAS/MAPK, PI3K/AKT and JAK/STAT5 signaling pathways, driving uncontrolled proliferation, apoptosis resistance and genomic instability. The development of tyrosine kinase inhibitors (TKIs) — imatinib, dasatinib, nilotinib, bosutinib and ponatinib — has dramatically improved patient outcomes, with life expectancy now approaching that of the general population. Therapeutic monitoring relies on standardized BCR-ABL1 transcript quantification by RT-qPCR on the International Scale (IS), enabling assessment of hematologic, cytogenetic and molecular responses (MMR, MR4, MR4.5) according to ELN 2020 guidelines. Digital PCR (dPCR) is an emerging complementary technology providing absolute quantification with superior sensitivity for deep residual disease monitoring. This bibliographic review offers a comprehensive synthesis of current knowledge, with particular emphasis on the epidemiological and clinical specificities of CML in the Algerian context.Type d'Item :Item, دور التحول الرقمي في تحسين جودة الخدمات المصرفية في البنوك التجارية(جامعة سطيف 1، كلية العلوم الاقتصادية والتجارية وعلوم التسيير، قسم علوم التسيير, 2026-09-10) بعداش، عبد الرؤوف; قرماش، عبد المنعمThis study was conducted within the framework of examining the impact of digital transformation on improving the quality of banking services, based on the growing importance of digital transformation as one of the fundamental pillars for enhancing banking performance and strengthening the competitiveness of banks in today's rapidly evolving digital environment. The study aimed to analyze the nature of the relationship between digital transformation and banking service quality, as well as to measure the extent to which the adoption of digital technologies contributes to improving the quality of services provided to customers and enhancing their satisfaction. To achieve the objectives of the study, the descriptive-analytical approach was adopted. A questionnaire was used as the primary instrument for data collection from a sample of customers of the banking institution under study, namely the Credit Populaire (CPA), Sétif Branch. The collected data were statistically analyzed using the Statistical Package for the Social Sciences (SPSS). A range of appropriate statistical techniques was employed, including frequencies, percentages, arithmetic means, standard deviations, validity and reliability tests, Pearson's correlation coefficient, and simple linear regression analysis. These techniques were used to test the study hypotheses and to determine the strength of the relationship and the effect between the study variables. The study was based on a main hypothesis stating that digital transformation has a statistically significant effect on improving the quality of banking services, from which several sub-hypotheses were derived. The findings revealed a positive and statistically significant impact of digital transformation on banking service quality. This result highlights the effective role of digital technologies in developing electronic banking channels, simplifying procedures, improving transaction processing speed, enhancing reliability and security, and facilitating access to banking services. These improvements contributed significantly to increasing customer satisfaction and strengthening customers' trust in the banking institution. In light of these findings, the study recommends accelerating the pace of digital transformation through greater investment in technological infrastructure, further development of digital banking services in line with customer expectations, continuous enhancement of human resource competencies through training, strengthening information security, and promoting digital awareness. These measures would contribute to achieving a sustainable competitive advantage and continuously improving the quality of banking services.Type d'Item :Item, دور التدقيق الداخلي في تعزيز نظام الرقابة الداخلية لتحسين فعالية دورة المشتريات(جامعة سطيف 1 فرحات عباس ، كلية العلوم الاقتصادية والتجارية وعلوم التسيير، قسم علوم المالية والمحاسبة, 2026-09-10) رزاقي، صبرينة; بريمي، منالAbstract This study aims to identify the role of internal auditing in strengthening the internal control system and improving the procurement cycle within an organization. Internal auditing is a crucial functionates management ensure the integrity of procedures, identify weaknesses, and provide recommendations that contribute to improving operations and achieving set objectives. Given the importance of the procurement cycle and its fund amental role within an organization, this study focuses on highlighting the extent to which internal auditing contributes to strengthening control over the various stages of the procurement process, from identifying needs to receiving purchases and settling payments. To achieve the study's objectives, a descriptive-analytical approach was adopted, examining the theoretical aspects related to internal auditing, internal control, and the procurement cycle, and then applying them to a practical field study at the Algerian Electricity and Gas Industries Company (SAIEG). The study's results how that internal auditing effectively contributes to strengthening the internal control system by monitoring compliance with approved procedures, identifying potential irregularities, and providing the necessary recommendations for performance improvement. The results also indicated that an effective internal control system helps improve the procurement cycle and ensures it simple mentation in a more organized and efficient manner. In light of these findings, the study recommended supporting and strengthening the internal audit function within the organization, while ensuring the implementation of its recommendations due to their positive impact on improving the internal control system and the procurement cycle.Type d'Item :Item, دور قائمة التدفقات النقدية في ترشيد قرارات التمويل في المؤسسة الاقتصادية(جامعة سطيف 1 فرحات عباس ، كلية العلوم الاقتصادية والتجارية وعلوم التسيير، قسم علوم المالية والمحاسبة, 2026-09-10) بن كعلول، روفيدة; بركات، أمينةAbstract: This study aimed to highlight the role of the statement of cash flows in rationalizing financing decisions within an economic institution, through the analysis of balances and financial ratios derived from it, the descriptive approach was adopted in the theoretical part to shed light on the various concepts related to cash flows and financing decisions, their importance, objectives, as well as the methods for calculating their indicators and financial ratios, meanwhile, the analytical approach and the case study method were employed in the practical part through a field study conducted at the High Plateaus Grains Branch in Setif during the period (2022-2024). The study concluded that the statement of cash flows is an effective tool in supporting financing decisions through the indicators it provides, which contribute to understanding the financial position of the institution, the results also showed that cash flow analysis is a key element in rationalizing financing decisions, as it provides a deep understanding of the level of liquidity available within the institution. Furthermore, the findings revealed that the institution under study has a good ability to generate liquidity from its operating activities, while adopting a cautious financing policy aimed at reducing the level of indebtedness.