Évaluation des Connaissances des Étudiants en Pharmacie sur la Pharmacovigilance

Abstract

Pharmacovigilance is a fundamental discipline for ensuring the safety and trustworthiness of medications. Its evolution over time has followed several stages: from early regulations in antiquity to the emergence of national drug monitoring agencies, alongside the reinforcement of pharmacovigilance within pharmaceutical companies, and the establishment of international exchanges concerning adverse drug effects. In this study, we set out to assess pharmacy students' knowledge of pharmacovigilance. In the first part, we describe the evolution of pharmacovigilance and its current functioning, including Phase IV studies, also known as post-marketing surveillance studies. We also delve into the classification of adverse effects. Subsequently, we delve into pharmacovigilance procedures, its foundations, and its missions, with a specific focus on pharmacovigilance in Algeria. We explore the general organization of pharmacovigilance and materiovigilance, the role of the pharmaceutical industry, and risk management, crucial knowledge for students. Additionally, we reference the latest recommendations from ANSM regarding pseudoephedrine-based medications. For evaluation, we utilized an online informative form filled out by students. Analyzing their responses enables us to identify gaps, either in understanding pharmacovigilance terminology or in the content of their curriculum. Consequently, this work aims to guide students towards a better understanding of pharmacovigilance and effective practice in managing medication-related adverse events.