Étude de décontamination d’une eau synthétique contenant le dextropropoxyphène (effluent pharmaceutique)

Abstract

This work deepens the study of the medical use of dextropropoxyphene, specifying its pharmacological properties, its various medical applications, as well as its toxicological implications. It also analyzes the challenges associated with the presence of drugs, including opioid analgesics, in wastewater, and explores treatment technique such as adsorption and high performance liquid chromatography (HPLC) as a dosing method. This work highlights the critical importance of these approaches to reducing environmental and public health risks, requiring continued research and innovative solutions. The results obtained using UV-VIS and HPLC do not show proportionality of absorbance and surface area with concentration, which makes it impossible to establish a calibration curve. In addition, the chromatograms obtained by HPLC are not reproducible. Several parameters were studied such as the nature of dissolution solvent, mobile phase, pH, column and DXP concentrations to improve the dosage but still no proportionality. The adsorption test carried out directly in two solutions of different pH, 3.9 and 7.3, showed after an infrared analysis of the solids the presence of DXP in the maghnite implying the adsorption of DXP by the maghnite of the two solutions.