Effet antioxydant de l’extrait aqueux des feuilles de Moringa oleifera Lam.

Abstract

Moringa Oleifera is an edible plant widely used in traditional medicine.The present work aims to evaluate the antioxidant activity of the aqueous extract of the leaves of this plant.The phytochemical study showed that the extract is rich in polyphenols and flavonoids. The evaluation of the antioxidant power by the DPPH test showed that the aqueous extract of has a strong antioxidant activity with an of IC50 86,25  4,05μg/ml. This activity is lowerthan that of BHA(IC50=86,15  1,12 μg/ml). The plantextractalso shows a powerful iron chelating effect (IC50= 57, 81 ± 8,26 μg/ml). Likewise, the extract has a good concentration-dependent reducing power with EC50 of 115, 86 0,884 μg/ml. The results of this study also show that the plant extract has a protective effect against membrane lysis induced in erythrocytes by AAPH. The best protection is exerted by 50 μg/ml of the extract with an HT50 of 2.13 ± 0, 12 hours. According to these results, it isfound that the extract of Moringa Oleifera has an important antioxidant activity, which confirms the pharmacological effects of this plant as a well as traditional use for therapeutic purposes.