Effets anti-inflammatoires et immunomodulateurs du pollen

Abstract

Pollen is a natural source rich in bioactive compounds, particularly polyphenols and flavonoids such as quercetin, which possess antioxidant, anti-inflammatory and immunomodulatory properties. These molecules regulate cellular pathways of inflammation and immune response by limiting the production of pro-inflammatory cytokines (TNF-α, IL-1β and IL-6) and modulating key mechanisms (NF-κB and MAPK). Pollen acts on immune cells (macrophages, lymphocytes and mast cells) by promoting controlled inflammation and stimulating both innate and adaptive immunity, thereby strengthening defense against pathogens while preventing chronic damage. Its anti-inflammatory effectiveness, comparable to certain medications, makes pollen a promising natural alternative for sustainably modulating inflammation and immunity