Les complications infectieuses posttransfusionnelles chez les enfants atteints du syndrome thalassémique-chu de Sétif

Abstract

Post-transfusion infectious complications are a major public health concern. A cross-sectional descriptive study conducted at the KAABOUB pediatric department of the Sétif University Hospital between November 2023 and March 2024 focuses on post-transfusion infectious complications in polytransfused children under 16 years old with thalassemia syndrome. The study included 27 patients with an average age of 8.63 years, 63% of them males and 27% females, mainly residing in Sétif. The majority came from middle-income families with parents having a secondary education level or less. 37% of the patients were from consanguineous marriages. All suffered from major betathalassemia , and 77.8% received monthly transfusions of leukoreduced and phenotyped red blood cellconcentrates. Additionally, 96.3% were on chelationtherapy.Regardingvaccinations,7.4% were immunized against pneumococcus (pneumo 23) and 100% against hepatitis B. 11% had late complications (all due to HCV), and 22% had immediate complications. The study highlights the importance of risk prevention, improving transfusion protocols and optimizing care for this population.