L’étude de l'effet des produits chimiques et des médicaments sur la fertilité

Abstract

Drugs use and exposure to chemicals are commonplace throughout the world, particularly in Algeria. They can be responsible for infertility, which is a major public health problem. This study aimed to identify drugs, chemicals and their effects on fertility in a local population in Sétif region. A survey of 103 subjects was carried out in the anti-cancer center and its chemotherapy preparation unit, as well as in the cytogenetics, toxicology and forensic medicine laboratory of Setif University Hospital. Information was collected using a questionnaire. Among the subjects, twenty-one (21) volunteers probably had fertility problems. Our results showed that infertility problems are encountered mainly in patients receiving chemotherapy treatments at Sétif cancer center. The volunteers' responses concerning chemical substances showed that the majority of infertile subjects were not exposed to any substance posing a risk to fertility. Further research is therefore needed to better understand the effect of chemical and medicinal substances on fertility in different contexts and populations. These results provide a database for future studies aimed at assessing the beneficial and harmful properties of individual drugs and chemicals on fertility.