Evaluation des Facteurs de Risque des Accidents Hémorragiques et de leur Evitabilité chez les Patients sous Antivitamines K CHU de Sétif
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Université Sétif1 Ferhat Abbas. Faculté de Médecine.
Abstract
Antivitamins K are anticoagulants administered orally used for the prevention of thromboembolic
diseases, in recent years there has been a significant increase in their uses. Progress has been made
to make this use safer, despite this treatment with antivitamins K still present a high percentage of
hemorrhagic accidents. We have realized a prospective study over 3 months at cardiology service
of university hospital center of Sétif. 25 patients, under antivitamins K and who presented a
hemorrhagic complication, were included. We sought the risk factors quoted in the literature. The
criteria of assumption of responsibility were studied and compared with those of the
recommendations of the “Haute autorité de santé” 2008.
We conducted a prospective study over a period of 3 months of 25 patients. The average age of our
patients is 71,6 with a sex ratio of 0.4. We note in our series multi- calibrated field antivitamins K
patients. Venous thromboembolic disease was the main indication identified. Externalized bleeding
was the most common. Conduct was different depending on the case based on the judgment of
antivitamins K , administration saw K , transfusion of red blood cells and fresh frozen plasma.
Polypharmacy, advanced age and associated defects were identified as risk factor for bleeding under
antivitamins K. Preventing the occurrence of imbalances is pillar of antivitamins K patients, hence
the importance and information and education of these patients to overcome the potentially lifethreatening iatrogenic complications of these patients.
