Hémophilie chez l'enfant Intérêt de la Prophylaxie Personnalisée Service de Pédiatrie CHU Sétif

Abstract

Hemophilia is a genetic bleeding disorder caused by a deficiency in factor VIII or factor IX. Improving the life expectancy of this population depends on adequate care. Our study is descriptive, retrospective from the medical files, the hospitalization registers of 76 hemophilia patients diagnosed, treated and followed in the pediatric department of the CHU of Sétif (Algeria) during the period from 2004 to 2020. The objective is to evaluate the therapeutic management of children with hemophilia in order to show the interest of personalized prophylaxis to improve this management. In this work we studied 15 variables providing information on the epidemiological characteristics of the patients and the therapeutic modalities (Sex, age, type, severity and prophylaxis, etc.). The results obtained stipulate that: All patients are male, 89.50% are under 11 years old with a predominance of hemophilia A (75%), 80.26% of these patients are severe hemophilias. Among the 58 patients who have prophylactic treatment, 20 patients are on personalized prophylaxis. This therapeutic method has led to a considerable reduction in the number of bleeds and an improvement in the quality of life of children with hemophilia