Extraction du collagène marin de type I à partir des Sous – produits du thon rouge.

Abstract

Collagen is an essential structural protein found in the connective tissues of animals. Due to its remarkable biological properties—notably its biocompatibility, biodegradability, and low immunogenicity—it offers significant potential for applications in the biomedical, pharmaceutical, food, and cosmetic sectors. This study focuses on the valorization of by-products from tuna (*Thunnus thynnus*)—specifically skin and bones—for the extraction of marine collagen. This work is part of a sustainable development initiative aimed at reducing waste from the fishing industry and producing high-value-added biomaterials. Collagen was extracted via acid solubilization, following an appropriate pre-treatment of the raw material. Two extraction methods were tested to evaluate their respective efficiencies in terms of extraction yield. The results indicate that the skin is the richest source of collagen, with a yield of 3.64% achieved using the first extraction method. For the bones, the first method yielded a very low 0.02%, whereas the second method resulted in a significant improvement, reaching 1.20%. These findings highlight the influence of the extraction method on the final yield and confirm the potential of tuna by-products as a promising source of marine collagen, thereby contributing to the sustainable valorization of marine resources.