Hémoglobinopathies a Sétif : Réalites Epidémiologiques et Profils Biologiques

Abstract

Hemoglobinopathies are inherited disorders resulting from qualitative or quantitative abnormalities of hemoglobin. This study aimed to describe the epidemiological and biological profile of patients diagnosed with hemoglobinopathies at Setif University Hospital. A total of 268 hemoglobin capillary electrophoresis profiles were analyzed using the MINICAP Flex Piercing system (SEBIA). Hemoglobin abnormalities were detected in 41% of cases, mainly represented by heterozygous β- thalassemia (35%), HbC trait (29%), and sickle cell trait (15%). These findings highlight the diversity of hemoglobinopathies in the region and the diagnostic value of capillary electrophoresis