Anti-Urolithiasis Activity of Herbal Folk Plants

Abstract

In the urinary system, urolithiasis is the most prevalent disorder which causes severe pain in individuals. Urinary stones are composed of calcium oxalate (CaOx) and calcium phosphate in approximately 80% of patients. Although various drugs and surgery operations are used to treat the disease, side effects of drugs and the high recurrence after therapy in patients cannot be ignored. Increasing incidence of the stone formation associated with inflammation and severe pain, the demand of medicinal plant treatement have gained more attention in preventing a suffering from lithiasis. The various herbal plants extract consist of active phytoconstituents like flavonoids, alkaloids, saponins, strerols possesses an bioactivity like diuretic, ant-inflammatory, analgesic and anti-oxidant property. The current study emphasizes the understanding pathology of the stone formation and traditional used medicinal plants as an alternative complementary therapy with less side effects. In addition, the study has also put an effort to summarize mechanisms of various herbal plants in the management of urolithiasis and providing a future investments and direction in developing plant based treatment for urolithiasis.