Étude ethnobotanique des plantes anthelminthiques et les propriétés antioxydantes deCucurbita pepo et Artemisia herba alba

Abstract

This study highlights the value of medicinal plants traditionally used to treat enterobiasis, a cosmopolitan intestinal helminthiasis caused by the nematode Enterobius vermicularis. An ethnobotanical survey was conducted among 35 individuals across five municipalities of the Sétif wilaya to collect local empirical knowledge regarding anthelmintic remedies. The results show that white wormwood (Artemisia herba-alba) is the most requested species by the population (53.66%), closely followed by Gymnocarpos decandrus (48.78%). In parallel, a quantitative and biological study was carried out on the aqueous extracts of four plants of interest: Glycyrrhiza glabra, Euphorbia guyoniana, Artemisia maritima, and Allium sativum. Spectrophotometric analysis revealed that Glycyrrhiza glabra has the highest total polyphenol content (70.65±0.35 mg GAE/g dry extract). Furthermore, the evaluation of the in vitro antioxidant activity using the DPPH• radical scavenging assay highlighted a strong antiradical capacity for Glycyrrhiza glabra, Artemisia maritima, and Allium sativum, comparable to the BHT standard, while Euphorbia guyoniana exhibited the lowest activity.