Bilan rénal et hépatique chez les femmes enceintes à risques

Abstract

Pregnancy is a sensitive period that requires close monitoring of physiological functions, particularly liver and kidney functions. This retrospective study examined 500 cases of high-riskpregnantwomen admitted to the "High-Risk Pregnancy" unit at the Mother and Child Hospital in Sétif between2020 and February 2025. The aim was to assess changes in liver (ALAT, ASAT, albumin) andkidney(creatinine, urea, uric acid) functions, taking into account several distribution parameters suchasage, geographic region, number of deliveries and miscarriages, pregnancy period, associated diseases, andannual distribution. The results showed that women aged between 25 and 35 years were themostvulnerable. Significant biological disturbances were observed among patients with hypertensionordiabetes, such as elevated liver enzymes, low albumin levels, and high uric acid levels, in additiontoisolated cases of electrolyte imbalances and a slight decrease in creatinine clearance. This studyhighlightsthe importance of regular and multidimensional biological monitoring of liver and kidney functionsinhigh-risk pregnant women to ensure early and effective medical care.