Activité antioxydante de Stipa tenacissima L. de la région d’Oum El Bouaghi

Abstract

Plante Stipa tenacissima L. is widely used in traditional medicine due to its multiple therapeutic effects. This study aimed to evaluate the phenolic content and antioxidant activity of this plant extract. Quantitative analysis showed that the ethanolic extract of S tenacissima is rich in polyphenols and flavonoids, with contents of 74.17 ± 0.14 mg gallic acid equivalents/g from the extract and 31.08 ± 0.69 mg quercetin equivalents/g from the extract. Antioxidant activity was evaluated using three methods: DPPH free radical scavenging, iron chelation, and reducing power. The results demonstrated the remarkable efficacy of the extract, with values of IC₅₀ = 0.07 ± 0.01 mg/ml, IC₅₀ = 1.050 ± 0.012 mg/ml and EC₅₀ = 0.13 ± 0.002 mg/ml respectively. Therefore, the ethanolic extract of S. tenacissima can be considered an important source of phenolic compounds that exert antioxidant activity through different mechanisms.