Etude phytochimique et évaluation in vitro de l’activité antioxydante de l’extrait méthanolique de la plante Centaurea sp.

Abstract

Centaurea species are traditionally used in some countries for the treatment of various ailments. This study aimed to evaluatein vitro the antioxidant potential of Centaurea sp. from the Algerian flora. The antioxidant properties of the methanolic extract were examined using different methods: free radical scavenging (DPPH and ABTS assays) and ferric reducing power. The total phenolic and flavonoid contents of the extract were determined using the Folin-Ciocalteu and aluminum chloride reagents, respectively. The methanolic extract of Centaurea sp., which was rich in polyphenols (308.61 ± 11.37 mg GAE/g extract) and total flavonoids (67.98 ± 2.79 mg QE/g extract), exhibited high antioxidant activity across all assays. A significant correlation was observed between antioxidant capacity and total phenolic content. These results suggest that this Centaurea species could be a promising source of novel antioxidants.